IDIOPATHIC APLASTIC ANEMIA

Dental management of idiopathic aplastic anemia: report of a case.

Long-term corticosteroid therapy of idiopathic aplastic anemia.

The results of a long-term corticosteroid therapy performed in 55 patients with idiopathic aplastic anemia are reported. Of these patients, cure was attained in 20 patients, remission in 5, and improvement in 10. The duration of the treatment of cured cases ranged from 138 to 1109 days with a median of 522 days. The results were much better than those with other treatments conventionally perfor...

Aplastic anemia.

PURPOSE OF REVIEW Most acquired aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and an empty bone marrow, which can be successfully treated with either immunosuppressive therapy or hematopoietic stem-cell transplantation. RECENT FINDINGS In aplastic anemia, oligoclonally expanded cytotoxic T cells induce apoptosis of hematopoietic ...

ALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA

Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...

Aplastic Anemia - Diagnos tics and Therapy of Acquired Aplastic Anemia